Chromatin state

Biomarker

1 paper

  • Animals1

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Science Translational Medicine

Fenofibrate improves cognition in chronic brain injury trial

In a randomized trial of 40 older adults with chronic traumatic brain injury, fenofibrate lowered plasma neurofilament light chain levels and improved cognitive function.In a randomized trial of 40 older adults with chronic traumatic brain injury, fenofibrate lowered plasma neurofilament light chain levels and improved cognitive function.

Randomised trial in 40 peopleInterventions
bioRxiv

DNMT3A mutations enhance macrophage migration in cells

Using human stem cell-derived macrophages, a preprint finds DNMT3A mutations derepress bivalent Polycomb target genes and enhance cell migration toward injured tissue.Using human stem cell-derived macrophages, a preprint finds DNMT3A mutations derepress bivalent Polycomb target genes and enhance cell migration toward injured tissue.

Preprint: experiments in human cellsDNMT3A