SOX2
Gene2 papers2 findingsHGNC 11195MGI 98364NCBI Gene 6657Taxon 9606
- Animals1
- Model organisms1
Interventions
1Kl knockout
downin mice1
1 study
Kl knockout
downin mice1
Kl knockout decreases SOX2 in mice.
Animalstongue epithelium
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice · Mechanisms of ageing and development · 24 Sep 2026
Effects
1NTF3
upin mouse cells1
1 study
NTF3
upin mouse cells1
SOX2 activates NTF3 in mouse cells.
Cells
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice · Mechanisms of ageing and development · 24 Sep 2026
Latest
2Neural stem cell exhaustion disrupts central nervous system renewal in aging colonial chordates
Researchers identified a conserved neural progenitor pool that drives weekly brain regeneration in Botryllus schlosseri but collapses during aging.Researchers identified a conserved neural progenitor pool that drives weekly brain regeneration in Botryllus schlosseri but collapses during aging.
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice
Researchers linked lower SOX2 to reduced neurotrophic factors and structural degradation in the tongue tissue of Klotho-deficient mice.Researchers linked lower SOX2 to reduced neurotrophic factors and structural degradation in the tongue tissue of Klotho-deficient mice.