Cell senescence

Biomarker

1 paper

  • Animals1

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UKRI | Medical Research Council£492.2k

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Aging Cell

Restoring a protein reduced DNA damage in human disc cells

Experiments that altered gene activity in human spinal disc cells found that restoring the protein also reduced senescence, a state in which cells stop dividing.Experiments that altered gene activity in human spinal disc cells found that restoring the protein also reduced senescence, a state in which cells stop dividing.

Experiments in human cellsDNA damage response
Atherosclerosis

Immune profile linked to heart artery disease in people with HIV

The high-inflammation group had 2.42 times the adjusted odds of substantial heart artery narrowing compared with the low-inflammation reference group.The high-inflammation group had 2.42 times the adjusted odds of substantial heart artery narrowing compared with the low-inflammation reference group.

Cross-sectional study of 651 peopleBiomarkers
Journal of Biochemical and Molecular Toxicology

Diesel-derived chemical triggers scarring signals in kidney cells

Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.

Experiments in cellsKidney