Cardiomyocyte proliferation

Papers on cardiomyocyte proliferation

44 papers4 new in 30 days

Sunday, November 1

Cell Reports

Exercise-linked protein promotes heart regeneration in mice

Experiments in adult mice found that giving clusterin, a protein increased by exercise, promoted heart regeneration after a heart attack.Experiments in adult mice found that giving clusterin, a protein increased by exercise, promoted heart regeneration after a heart attack.

Figure from Cell Reports
Mouse studyExercise

Monday, October 26

ESC Congress 2026 Abstract

Immune cell group helps repair hearts in newborn mice

Experiments in newborn mice found that removing these cells reduced heart muscle cell multiplication and worsened inflammation and scarring after heart attacks.Experiments in newborn mice found that removing these cells reduced heart muscle cell multiplication and worsened inflammation and scarring after heart attacks.

Heart cross-sections beside a newborn mouse show intact muscle with macrophages and scarred muscle crowded with inflammatory cells.

Tuesday, October 20

Nature Communications

Two immune responses aid heart regrowth in surface-dwelling fish

Researchers compared regenerating surface-dwelling Mexican cavefish with scar-forming cave-dwelling fish, then disrupted immune activity to test its role in repair.Researchers compared regenerating surface-dwelling Mexican cavefish with scar-forming cave-dwelling fish, then disrupted immune activity to test its role in repair.

Prolonged inflammation after cardiac injury is required for successful repair in surface fish hearts.
Fish studyImmune response

Friday, October 16

Friday, September 11

bioRxiv

Blocking a receptor lets a hormone spur mouse heart cell division

Experiments in newborn mouse heart cells found that blocking one hormone receptor allowed corticosterone to promote division through another, with effects depending on…Experiments in newborn mouse heart cells found that blocking one hormone receptor allowed corticosterone to promote division through another, with effects depending on surrounding cells.

Physiological glucocorticoids promote proliferation of GR-deficient neonatal cardiomyocytes.
Preprint: animal cell studyMechanisms

Tuesday, August 11

Thursday, August 6

Nature Cardiovascular Research

Lower workload spurred heart muscle cell division in animals

Animal transplant experiments kept adult hearts supplied with blood but not pumping, prompting heart muscle cells to multiply.Animal transplant experiments kept adult hearts supplied with blood but not pumping, prompting heart muscle cells to multiply.

Animal studyInterventions

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