Atretic follicles

1. Tea polyphenols decrease atretic follicles in rats (43.4 +/- 5.9 vs 79.7 +/- 7.5, p < 0.001).

   “significantly fewer atretic follicles were observed in the tea polyphenol group (43.4 +/- 5.9 vs 79.7 +/- 7.5; p < 0.001)”

   Animalsintragastric administrationovary4 monthsfemales

   Effects of plant polyphenols on ovarian follicular reserve in aging rats

   Biochemistry and cell biology = Biochimie et biologie cellulaire·1 Aug 2010

2. Tea polyphenols decrease atretic follicles in rats.

   “In the 3- and 10-month-old rat ovaries, the number of primordial follicles augmented, whereas that of atretic follicles decreased after the treatment for 4 weeks.”

   Animalsovary4 weeks

   Effects of tea polyphenols on ovarian development in rats

   Journal of endocrinological investigation·1 Dec 2008

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1. Resveratrol decreases atretic follicles in rats (51.0 +/- 6.2 vs 79.7 +/- 7.5, p < 0.01).

   “and fewer atretic follicles (respectively, 58.4 +/- 8.0, p < 0.05; and 51.0 +/- 6.2, p < 0.01) than controls”

   Animalsintragastric administrationovary4 monthsfemales

   Effects of plant polyphenols on ovarian follicular reserve in aging rats

   Biochemistry and cell biology = Biochimie et biologie cellulaire·1 Aug 2010

More on Resveratrol

1. Genistein decreases atretic follicles in rats (58.4 +/- 8.0 vs 79.7 +/- 7.5, p < 0.05).

   “fewer atretic follicles (respectively, 58.4 +/- 8.0, p < 0.05; and 51.0 +/- 6.2, p < 0.01) than controls”

   Animalsintragastric administrationovary4 monthsfemales

   Effects of plant polyphenols on ovarian follicular reserve in aging rats

   Biochemistry and cell biology = Biochimie et biologie cellulaire·1 Aug 2010

More on Genistein