An observational study of 110 adults aged 65–88 with depression found separate, additive links to amyloid, a protein, only in carriers of a genetic variant.An observational study of 110 adults aged 65–88 with depression found separate, additive links to amyloid, a protein, only in carriers of a genetic variant.
Persistent severe isolation was linked to higher levels of a blood marker of nerve-cell injury than no isolation, with a statistical association estimate of 0.31.Persistent severe isolation was linked to higher levels of a blood marker of nerve-cell injury than no isolation, with a statistical association estimate of 0.31.
In 957 non-demented adults, social isolation was associated with lower cognitive scores, decreased cerebrospinal fluid amyloid-beta levels, and higher tau-to-amyloid…In 957 non-demented adults, social isolation was associated with lower cognitive scores, decreased cerebrospinal fluid amyloid-beta levels, and higher tau-to-amyloid ratios.