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APOE‐ ɛ4 Moderates the Association between HDL‐c and White Matter Hyperintensity Volume
AAIC 2025 Abstract
Abstract
Background: Homozygous APOE‐ ɛ4 carriers have exhibited heightened white matter hyperintensity (WMH) burden based on severity ratings (Rojas et al., 2018). A higher high‐density lipoprotein cholesterol (HDL‐c) to low‐density lipoprotein cholesterol (LDL‐c) ratio is associated with less severe WMHs (Wei et al., 2023).
The paper
Zoe E. Tsokolas, Amaryllis A. Tsiknia, Melissa E. Petersen, Meredith N. Braskie
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Arthur W. Toga, Hussein N. Yassine, Sid E. O’Bryant, Kristine S. Yaffe, Kevin King, Matthew Borzage,University of Southern California
AAIC 2025 Abstract · 8 Jan 2026 · CC BY
Presented at AAIC 2025
