Amyloid-beta deposition

4 papers2 findings

Human trial1
Humans1
Animals1

Upstream

1

APOE

upin humans1

1 study

APOE increases amyloid-beta deposition in humans.
“amyloid-β deposition was more pronounced in peri-menopausal and post-menopausal women carrying apolipoprotein E-4 (APOE-4) genotype”
Humansperi-menopausal and post-menopausal women carrying APOE-4brainfemales
Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition
Scientific reports9 Jun 2021

Associations

1

Clusterin

upin humans1

1 study

Clusterin predicts amyloid-beta deposition in humans.
“elevated plasma levels of CLU in healthy older adults may precede significant Aβ deposition in the brain by as much as ten years”
Review
Clusterin as a biomarker for Alzheimer's disease
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2026

More on Clusterin

Latest

1 in 12 months

Zhurnal Nevrologii I Psikhiatrii Imeni S.S Korsakova7 Aug

Clusterin as a biomarker for Alzheimer's disease

Systematic reviewAlzheimer's disease

Nature6 Aug

Lithium deficiency and the onset of Alzheimer's disease

Experiments in miceMechanisms

IMeta21 Feb

Time-restricted feeding mitigates Alzheimer's disease-associated cognitive impairments via a B. pseudolongum-propionic acid-FFAR3 axis

Non-randomised trial in peopleDietary restriction

Scientific Reports9 Jun

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

Cohort study in peopleOxidative phosphorylation

Human Brain Mapping6 May

Network interdigitations of Tau and amyloid-beta deposits define cognitive levels in aging

Cohort study in peopleBiomarkers