Age-associated gene expression
1 paper1 finding
- Cells1
Interventions
1Chemical reprogramming
downin human cells1
1 study
Chemical reprogramming
downin human cells1
Chemical reprogramming decreases age-associated gene expression in human cells.
“Both reprogramming methods reduced senescence, mitochondrial ROS, and age-associated gene expression, with chemical reprogramming matching or exceeding OSKM efficacy.”
Cellsprogerin-induced aged fibroblasts and primary fibroblasts from donors over 85human-optimized protocolfibroblast
bioRxiv (Cold Spring Harbor Laboratory)1 Dec 2025Preprint
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