Adropin

1. Adropin improves reaction time in rhesus monkeys.

   “Animals with higher adropin levels exhibited faster improvement in reaction time and reductions of variability in reaction time”

   Animals

   Low circulating adropin concentrations identify vulnerability in learning-dependent cognitive performance in aged rhesus macaques

   npj aging·10 Jun 2026

1. Adropin is associated with decision-making in rhesus monkeys.

   “low plasma adropin concentrations associate with poor decision-making in aged rhesus macaques subject to an increasing food choice test paradigm”

   Animalsplasma

   Low circulating adropin concentrations identify vulnerability in learning-dependent cognitive performance in aged rhesus macaques

   npj aging·10 Jun 2026

1. Type 2 diabetes is associated with adropin in humans.

   “Compared with controls, participants with T2DM had higher ePWV, older estimated arterial age, larger age gap, lower adropin, and higher oxLDL (all p < 0.001).”

   Humanstype 2 diabetes mellitus compared with age- and sex-matched controlsn = 300

   Development of a biomarker-enhanced arterial age model for young-to-middle-aged adults with type 2 diabetes

   Scientific reports·30 May 2026

More on Type 2 diabetes

1. Adropin is associated with early vascular aging in humans (OR 0.991 per pg/mL).

   “adropin (OR 0.991 per pg/mL; p < 0.001) and ET-1 (OR 1.017 per pg/mL, p = 0.005) remained independently associated with EVA.”

   HumansFully adjusted model in adults with T2DM and age/sex-matched controlsn = 300

   Adropin and Endothelin-1 as Complementary Signals Associated with Early Vascular Aging in Middle-Aged Type 2 Diabetes

   Diseases (Basel, Switzerland)·9 Apr 2026

More on Early vascular aging