Adropin

Adropin has been studied in 2 papers since 2021: none in people yet, 1 in animals, 1 review. The research so far is in animals. The newest paper, Dec 27, 2022: “Senescence-Associated Secretory Phenotype of Cardiovascular System Cells and Inflammaging: Perspectives of Peptide Regulation”.

Intervention

2 papers study it2 findingsUpdated

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: National Institute of Neurological Disorders and Stroke and others
  • Animals1

What did studies of Adropin find?

2

Studies of Adropin measured 2 outcomes; the most studied are neurotrophic responses (1 study) and cognitive function (1).

Neurotrophic responses

upin cells1

1 study
  1. Adropin increases neurotrophic responses in cells.

    “Potent neurotrophic responses in primary cultured neurons are consistent with adropin supporting the development and function of neural networks”

    Cellsprimary cultured neurons

    Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

    NPJ aging and mechanisms of disease

Cognitive function

upin mice1

1 study
  1. Adropin improves cognitive function in mice.

    “Treatment with synthetic adropin peptide also reversed age-related declines in cognitive functions”

    Animalssynthetic peptide

    Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

    NPJ aging and mechanisms of disease

Funding

1 grant since 2018

National Institute of Neurological Disorders and StrokeUS$416.6k

Latest