Papers by Ran Ran

139 results

  1. Nature Communications

    Probiotic shortened gut transit time in older adults

    A randomised, double-blind trial also found changes in gut bacteria, including suppression of bacteria that produce an enzyme involved in processing bile acids.A randomised, double-blind trial also found changes in gut bacteria, including suppression of bacteria that produce an enzyme involved in processing bile acids.

    Randomised trial in peopleGut and microbiome
  2. JCI Insight

    Antibody reduced fat while preserving lean mass in mice

    Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.

    Experiments in miceInterventions
  3. Functional & Integrative Genomics

    Blood taurine linked to common and rare DNA variants

    An analysis of 36,490 European individuals identified six regions with common DNA variants and two with rare variants associated with blood taurine levels.An analysis of 36,490 European individuals identified six regions with common DNA variants and two with rare variants associated with blood taurine levels.

    Study of 36,490 peopleMechanisms
  4. BMC Public Health

    Higher neuroticism links to broad disease risks in Chinese adults

    In 25,041 Chinese adults, high neuroticism scores were linked to 1.17- to 1.81-fold higher risks of major physical and mental conditions compared to low scores.In 25,041 Chinese adults, high neuroticism scores were linked to 1.17- to 1.81-fold higher risks of major physical and mental conditions compared to low scores.

    Cohort study of 25,041 peoplePopulations
  5. HGG Advances

    Summary-level genetic method improves Alzheimer's risk prediction

    The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk…The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk prediction.

    Computational studyAlzheimer's disease
  6. Poultry Science

    FOXO3 delays primordial follicle activation in chickens

    Germline chimeric chickens overexpressing FOXO3 maintained more dormant primordial follicles up to 21 days post-hatch alongside suppressed PI3K/AKT signaling.Germline chimeric chickens overexpressing FOXO3 maintained more dormant primordial follicles up to 21 days post-hatch alongside suppressed PI3K/AKT signaling.

    Experiments in chickensFOXO3
  7. JAMA Neurology

    Hearing aids did not cut dementia conversion in older adults

    Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.

    Randomised trial in 703 peopleDementia