Humans160 participants1 month
Effects of Rhythm Control versus Rate Control on Atrial Fibrillation and Frailty Development in Older Patients: Protocol for the Cardioversion of Atrial Fibrillation and Frailty in the Elderly (CAFFE) Study, an Observational, Prospective Cohort Study
JMIR Research Protocols
Abstract
Background Atrial fibrillation (AF), highly prevalent in older individuals, is associated with frailty and disability. AF therapy is based on rhythm control (RhythmC) to restore sinus rhythm or rate control (RateC) to lower the heart rate. Published guidelines do not indicate a preference for one over the other for older people.
The paper
Elisa Berni, Veronica De Angelis, Emanuele Santamaria, Stefano Fumagalli
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Alessandro Mengozzi, Claudia Di Serio, Giulia Spanalatte, Michele Biagioli, Arianna Tariello, Marta Niccolini, Camilla Cagnoni, Djullye Miduri Da Silva Nakano, Giada Alla Viligiardi, Marco Capacci, Andrea Ungar, Giancarlo la Marca, Igor Diemberger, Agostino Virdis,University of Florence
JMIR Research Protocols · 29 Sep 2026 · CC BY
