Humans49,201 participantsCohort study

Additive Burden of Low Peak Expiratory Flow and Sleep Disturbance on Incident Depressive Symptoms in Later Life: A Four-Cohort Longitudinal Study of 49,201 Participants

Figure 1. Study design. Baseline assessment of peak expiratory flow and sleep disturbance at each cohort’s baseline wave; classification into four mutually exclusive joint exposure groups; cohort-specific…
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Figure 1. Study design. Baseline assessment of peak expiratory flow and sleep disturbance at each cohort’s baseline wave; classification into four mutually exclusive…Study design. Baseline assessment of peak expiratory flow and sleep disturbance at each cohort’s baseline wave; classification into four mutually exclusive joint exposure groups; cohort-specific follow-up schedules; and the analytic approach, comprising Poisson generalized…Li et al. · CC BY

Healthcare

Abstract

Background Lung function and sleep are each prospectively associated with late-life depressive symptoms, but whether their co-occurrence carries risk beyond the sum of the two components has not been tested across national populations.

The paper

Peking University Cancer Hospital

Healthcare · 10 Sep 2026 · CC BY

doi.org/10.3390/healthcare14182951PubMed 42793490