microRNA-7-5p and α-Synuclein SAA Predict Parkinson's Disease Phenoconversion

Figure 1. Survival curves for phenoconversion of prodromal Parkinson's disease patients based on data‐derived cutpoints.
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Figure 1. Survival curves for phenoconversion of prodromal Parkinson's disease patients based on data‐derived cutpoints.Survival curves for phenoconversion of prodromal Parkinson's disease patients based on data‐derived cutpoints.Zadegan et al. · CC BY

Annals of Clinical and Translational Neurology

Abstract

Objective Corroborate blood neuron-derived extracellular vesicle (NDEV) alpha-synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn-SAA), and blood microRNA-7-5p (miR-7-5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be mo

The paper

University of Tennessee Health Science Center

Annals of Clinical and Translational Neurology · 25 Sep 2026 · CC BY

doi.org/10.1002/acn3.70539PubMed 42791197