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The Link Between Exercise and Diminishing Body Metabolism: How Pre/Probiotics Help Maintain a Healthy Aging Process

Preprint: reviewInterventions
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Abstract

Declining whole-body and skeletal muscle protein metabolism is frequently linked to ageing, which can lead to metabolic diseases, sarcopenia, and decreased muscle mass. Slower metabolic processes and a higher risk of chronic diseases result from this reduction. Through increased muscle protein synthesis and improved inter-organ metabolic coordination, aerobic exercise has been demonstrated to partially counteract these effects. Prebiotics and probiotics have been shown to modulate the gut microbiota, which in turn affects systemic inflammation, nutrient absorption, and overall metabolic health. This article explores the ways in which gut microbiome-targeting therapies, such pre/probiotics, and exercise can complement one another to maintain metabolic function and encourage better ageing.

The paper

(Deemed to be University); Pt. Jawahar Lal Nehru Memorial Medical College

Preprints.org, 11 Jul 2025, CC BY, Preprint, not peer-reviewed

doi.org/10.20944/preprints202507.0925.v1