GeroScience
Two mole-rat species resist skin cancer but differ in immune response
Damaraland mole-rats developed no tumors over more than three years, while their immune response to cancer-causing chemicals differed from that of naked mole-rats.Damaraland mole-rats developed no tumors over more than three years, while their immune response to cancer-causing chemicals differed from that of naked mole-rats.
Animal studyImmune response
Who was studiedDamaraland and naked mole-rats, 1 week, against carcinogen-exposed naked mole-rats
What changedMore immune cells entered carcinogen-exposed skin in Damaraland mole-rats than in naked mole-rats
The catchDamaraland mole-rats’ abundant hair follicles can influence skin immune cell recruitment independently of cancer resistance