National Natural Science Foundation of China

• NCT07555405

  Collaborator, Phase 4, Not yet recruiting, 6 people, 29 Apr 2026

• NCT06604611

  Collaborator, Phase 4, Status unknown, 200 people, 19 Sept 2024

• NCT05814770

  Collaborator, Phase 4, Status unknown, 96 people, 18 Apr 2023

• NCT05700266

  Collaborator, Phase 2/3, Status unknown, 1,180 people, 26 Jan 2023

• NCT04850950

  Collaborator, Phase 4, Status unknown, 240 people, 20 Apr 2021

• NCT04661709

  Collaborator, Phase 4, Status unknown, 502 people, 10 Dec 2020

• NCT03260166

  Collaborator, Phase 2, Status unknown, 40 people, 24 Aug 2017

• NCT03078257

  Collaborator, Phase 1, Status unknown, 90 people, 13 Mar 2017

• NCT02484027

  Collaborator, Phase 4, Status unknown, 456 people, 29 Jun 2015

• NCT02447809

  Collaborator, Phase 4, Status unknown, 400 people, 19 May 2015

• NCT02435654

  Collaborator, Phase 4, Completed, 128 people, 6 May 2015

• NCT02383771

  Collaborator, Phase 4, Completed, 64 people, 9 Mar 2015

• NCT02303873

  Collaborator, Phase 4, Completed, 99 people, 1 Dec 2014

• NCT01974336

  Collaborator, Phase 4, Completed, 30 people, 1 Nov 2013

• NCT01182662

  Collaborator, Phase 2, Status unknown, 30 people, 17 Aug 2010

• NCT01129739

  Collaborator, Phase 2, Status unknown, 30 people, 25 May 2010

• Dose-Response Relationship Between Physical Activity and Intrinsic Capacity Decline Among Hospitalised Older Patients

  72474092, 1 Dec 2026

• Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

  82174410, 82474541, 82230119, 82104497, 15 Oct 2026

• Docosahexaenoic acid remodels lipid composition of lipid rafts and mitochondrial function in ApoE4/4 mouse brain: a multi-omic investigation

  82173508, 15 Oct 2026

• Personalized haemodynamic modelling for non-invasive quantification of arterial stiffness in the human vasculature

  U2241210, 14 Oct 2026

• Transition-Specific Associations of Cardiometabolic Biomarker Burden With Cardio-Renal-Metabolic Multimorbidity Progression: A Multistate Cohort Study

  82173905, 14 Oct 2026

• Suppressing neural stem cell PLA2G7 restores inhibitory circuit function and improves cognition in aging mice

  32170990, 32371031, 14 Oct 2026

• Interpretable Source-Aware Bone-Muscle Fusion Framework for Multicenter Prediction of Osteoporotic Vertebral Fractures

  82460361, 12261027, 13 Oct 2026

• A Dual-Functional Nanoplatform Targeting the dsDNA-cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

  82402798, 82472484, 32471431, 82572825, 12 Oct 2026

• Cellular Senescence in Heart Failure with Preserved Ejection Fraction: Mechanisms and Therapeutic Opportunities

  82374195, 12 Oct 2026

• Tumor-Associated Immunosenescence: Mechanisms, Biomarkers, and Age-Adaptive Immunotherapy

  82472636, 12 Oct 2026

• Metagenomic and systematic analyses reveal the association between hemoglobin levels and metabolic disorders: an open cohort study of Tibetan adults in Qinghai Plateau

  U24A20774, 72364032, 12 Oct 2026

• Upper cervical spinal cord morphometric charts: from population references to individualized clinical assessment

  82572171, 12 Oct 2026

• Duration-related regional patterns of gray matter alterations in hypertension and their cognitive implications

  62522119, 12 Oct 2026

• A Novel Reactive Oxygen Species-Responsive Bone-Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy-Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

  82202757, 52473126, 82372461, 32301097, 11 Oct 2026

• Scalable methylome-transcriptome profiling resolves clonal organization in human hematopoiesis

  32470700, 11 Oct 2026

• Constructing hypoxia and bioshield inhibits neurovascularized endochondral ossification for stable cartilage regeneration

  82472153, T2522021, 82402942, 82471886, 10 Oct 2026

• Development and validation of a machine learning model for screening individuals at high risk of self-reported osteoporosis among community-dwelling older adults: a cross-sectional study

  72574108, 10 Oct 2026

• Esophageal squamous cell carcinoma prevention in high-risk, resource-limited rural China: Dysplasia screening and modifiable risk factors in a 14-year follow-up study

  82204030, 82473624, 10 Oct 2026

• Beyond the brain-centric view: A systems physiology framework for exercise-induced neuroprotection in Alzheimer's disease

  10 Oct 2026

• Divergent associations of weekly and seasonal sleep variability with 1-year glycemic change in Chinese adults

  82373673, 10 Oct 2026

Sources: api.crossref.org, pubmed.ncbi.nlm.nih.gov

• Esophageal squamous cell carcinoma prevention in high-risk, resource-limited rural China: Dysplasia screening and modifiable risk factors in a 14-year follow-up study

  Grants or research support, 10 Oct 2026

• Short-Term Audiometric Trajectories in Older Adults Receiving Systemic Human Umbilical Cord-Derived Mesenchymal Stem Cells: An Exploratory Single-Arm Substudy

  Grants or research support, 26 Sept 2026

• Circulating vitamin D metabolites are distinctly associated with all-cause and cardiovascular mortality: a prospective study

  Grants or research support, 16 Sept 2026

• SIRT3-dependent mitochondrial redox homeostasis protects against age-related tendon degeneration

  Grants or research support, 9 Sept 2026

• Biomaterials for intervertebral disc regeneration: Niche reprogramming, precision therapeutics, and structural reconstruction

  Grants or research support, 3 Sept 2026

• Muscle health and cardiovascular risk across stages of Cardiovascular-Kidney-Metabolic syndrome: A prospective cohort study

  Grants or research support, 23 Aug 2026

• Osthol ameliorates Alzheimer's disease-associated cognitive impairment by targeting the estrogen-cholinergic axis in age-stratified female 3×Tg-AD mice

  Grants or research support, 13 Aug 2026

• Incidence of type 2 diabetes mellitus in men receiving finasteride and tamsulosin: a cross-validation cohort study using data from China and UK populations

  Grants or research support, 6 Aug 2026

• Risk Factors for All-Cause and Cause-Specific Mortality in Patients with Chronic Kidney Disease: Age-Specific Associations and Attributable Burden

  Grants or research support, 10 Jul 2026

• Polylactic acid microplastic exposure induced male reproductive toxicity and decreased testosterone levels by accelerating Leydig cell senescence

  Grants or research support, 7 Feb 2026

• Adipose-derived mesenchymal stem cell exosomes enhance diabetic wound healing via the amelioration of fibroblast senescence through the SMARCAL1-Drp1 signaling pathway

  Grants or research support, 6 Feb 2026

• Biological Age Acceleration and All-Cause Mortality in Moderate to Severe Aortic Valve Stenosis: A Prospective Cohort Study

  Grants or research support, 31 Jan 2026

• Ailanthone hijacks ERK/NF-κB cascade to attenuate osteoclastogenesis for osteoporosis

  Grants or research support, 22 Jan 2026

• PTPN2 alleviates Silicotic pulmonary fibrosis by inhibiting senescence of type II alveolar epithelial cells via retinol metabolism regulated by ALDH1A2

  Grants or research support, 19 Jan 2026

• Mechanosensitive Yes-Associated Protein/TAZ-cGAS-STING Axis Induces Periodontal Ligament Fibroblasts Senescence and Mediates Compression-Induced Root Resorption

  Grants or research support, 11 Dec 2025

• Transitions of loneliness and lonely life expectancy: A longitudinal study across 24 countries

  Grants or research support, 20 Aug 2025

• Depressive symptoms and mild behavioral impairment among patients with late-life depression in nursing homes: the mediating and moderating effects of sleep quality and social support

  Grants or research support, 20 Aug 2025

• Parthanatos: A redox-dependent cell death pathway in cardiovascular disease and myocardial aging

  Grants or research support, 15 Aug 2025

• Association between visceral fat accumulation and sarcopenia: A cross-sectional study

  Grants or research support, 30 Jul 2025

• High-frequency quantitative ultrasound in characterizing human skin aging: an exploration of the non-modeling and modeling approaches

  Grants or research support, 30 Jun 2025

Sources: pubmed.ncbi.nlm.nih.gov

• Age-related changes of FCGR3A+ natural killer cells and their association with elderly atopic dermatitis

  EBioMedicine, 22 Sept 2026

• Cardiovascular-kidney-metabolic syndrome and the risk of liver-related and cardiovascular events across the steatotic liver disease spectrum

  Med (New York, N.Y.), 9 Sept 2026

• The human oral and airway viral genome catalog from metagenomes enables virome characterization informing respiratory health

  Med (New York, N.Y.), 3 Sept 2026

• Monitoring ovarian reserve dynamics via a high-sensitivity anti-Müllerian hormone assay in premenopausal breast cancer patients undergoing chemotherapy

  Human reproduction (Oxford, England), 28 Aug 2026

• Preconception 1-hour blood glucose as an early indicator of gestational diabetes mellitus risk in PMOS/PCOS women undergoing IVF treatment: a multi-centre cohort study

  Human reproduction (Oxford, England), 10 Aug 2026

• AI-driven therapeutic antisense oligonucleotide for processing-deficient progeroid laminopathies

  Med (New York, N.Y.), 2 Jul 2026

• GLP-1R in JBMMSCs Suppressed Jaw Bone Osteoporosis via Modulating PKA/STAT3/TET3/SHP2/ß-catenin Signaling–Induced Osteoblast Differentiation

  ADA Scientific Sessions 2026 abstract, 6 Jun 2026

• ANGPTL8 Promotes Endothelial Senescence in Type 2 Diabetes via RTN4R-PI3K/AKT/FOXO3A

  ADA Scientific Sessions 2026 abstract, 6 Jun 2026

• The Clinical Outcomes of Preclinical and Clinical Obesity across Multiple Cohorts

  ADA Scientific Sessions 2026 abstract, 6 Jun 2026

• In-Hospital Mortality among Patients with Diabetes During and After the COVID-19 Pandemic: A Population-Based Study

  ADA Scientific Sessions 2026 abstract, 6 Jun 2026

• Unraveling the Metabolic–Cardiovascular Disease Nexus: An Epidemiological Network Analysis Identifies Central Indicators

  ADA Scientific Sessions 2026 abstract, 6 Jun 2026

• A Novel Dual-Endpoint Model to Simultaneously Predict Risks of Type 2 Diabetes and Cardiovascular Disease in Prediabetes

  ADA Scientific Sessions 2026 abstract, 6 Jun 2026

• Physical Activity Mitigates Genetic Obesity Risk via the Leptin–Adiponectin Axis in Children and Adolescents: Findings from the BCAMS Study and Multiomics Analysis

  ADA Scientific Sessions 2026 abstract, 5 Jun 2026

• Liraglutide Ameliorates Diabetic Cardiomyopathy via Ferroptosis Inhibition: Clinical CMR Evidence and Mechanistic Insights

  ADA Scientific Sessions 2026 abstract, 5 Jun 2026

• Effect of Tirzepatide on Cardiac Arrhythmia in Adults with Type 2 Diabetes and Obesity: A Systematic Review and Meta-Analysis

  ADA Scientific Sessions 2026 abstract, 5 Jun 2026

• Where Fat Is Stored Matters More than How Much: A Large-Scale Population-Based Study Integrating DXA Phenotyping and Causal Inference

  ADA Scientific Sessions 2026 abstract, 5 Jun 2026

• Is Uric Acid Excretion A Possible Cause of Chronic Kidney Disease? A Cross-Sectional Study of CHNS with Mendelian Randomization Verification

  ADA Scientific Sessions 2026 abstract, 5 Jun 2026

• Trends of PM2·5-attributable dementia deaths in the context of population ageing in China, 2000-60: a health impact assessment

  The lancet. Healthy longevity, 9 May 2026

• Phenotypic age acceleration and early-onset lung cancer: a case-control and prognostic cohort study involving multiple clinical centres with validation in the UK Biobank

  EBioMedicine, 12 Feb 2026

• Association between different dietary patterns and the risk of major brain disorders: a prospective multi-cohort study

  EClinicalMedicine, 17 Nov 2025