Trans-zeatin
Intervention1 paper5 findingsPubChem 449093ChEBI 15333
- Animals1
Outcomes
5PI3K–AKT signalling
downin mouse cells1Very low certainty
1 study
PI3K–AKT signalling
downin mouse cells1Very low certainty
Trans-zeatin inhibits PI3K–AKT signalling in mouse cells.
Cellsosteoclastogenesis
Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling · Biochemical pharmacology · 25 Sep 2026
Reactive oxygen species
downin mouse cells1Very low certainty
1 study
Reactive oxygen species
downin mouse cells1Very low certainty
Trans-zeatin decreases reactive oxygen species in mouse cells.
Cellsin osteoclasts
Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling · Biochemical pharmacology · 25 Sep 2026
Bone loss
downin mice1Very low certainty
1 study
Bone loss
downin mice1Very low certainty
Trans-zeatin decreases bone loss in mice.
Animalsovariectomy-induced
Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling · Biochemical pharmacology · 25 Sep 2026
Bone resorption
downin mouse cells1Very low certainty
1 study
Bone resorption
downin mouse cells1Very low certainty
Trans-zeatin decreases bone resorption in mouse cells.
Cellsin vitro
Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling · Biochemical pharmacology · 25 Sep 2026
Osteoclastogenesis
downin mouse cells1Very low certainty
1 study
Osteoclastogenesis
downin mouse cells1Very low certainty
Trans-zeatin inhibits osteoclastogenesis in mouse cells.
Cellsin vitro
Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling · Biochemical pharmacology · 25 Sep 2026