Social stress

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

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1 lab in 1 country

Humans1

Associations

Mortality

upin humans1HR 1.1

1 study

Social stress is associated with mortality in humans (HR 1.10, 95% CI 1.04–1.17).
HumansHigh–high versus low–high social stress trajectory; fully adjusted modeln = 10,938
High, rising social stress linked to death risk in older adults
BMC geriatrics9 Oct 2026

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1 in 12 months

BMC Geriatrics1 h

High, rising social stress linked to death risk in older adults

The adjusted hazard ratio, which compares death rates over time, was 1.10 for consistently high, rising social stress versus initially lower, rising stress.The adjusted hazard ratio, which compares death rates over time, was 1.10 for consistently high, rising social stress versus initially lower, rising stress.

Cohort study of 10,938 peoplePopulations

Paper