Healthy lifestyle

1. Healthy lifestyle improves healthspan in humans (Men: 4.78 years vs. Women: 5.26 years).

   “participants with 4‐5 healthy lifestyle factors substantially extend cognitively health life expectancy (Men: 4.78 years vs. Women: 5.26 years)”

   Humans4‐5 vs. 0‐1 healthy lifestyle factors15 yearsn = 6,488

   Healthy lifestyle factors outweigh influence of APOE genetic risk on extending cognitively healthy life expectancy · AAIC 2025 abstract · 23 Dec 2025

1. Healthy lifestyle lowers the risk of kidney stone disease in humans (HR 0.51, 95% CI 0.44-0.59).

   Humansmedian follow-up of 12.3 yearsn = 300,875

   Healthy Lifestyle, Genetic Susceptibility and Risk of Kidney Stone Disease in the UK Biobank: A Prospective Cohort Study · Mayo Clinic proceedings · 18 Sep 2026

Kidney stone disease →

1. Healthy lifestyle lowers the risk of lung cancer in humans (HR 0.34, 95% CI: 0.30-0.38).

   Humansmedian of 11.69 yearsn = 254,874

   Combined association of genetic predisposition and healthy lifestyle with lung cancer risk: a population-based cohort study · Translational lung cancer research · 14 Jul 2026

Lung cancer →