Social engagement

Intervention2 papers3 findings

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

2 independent labs in 2 countries

Funders: National Institute on Aging and 5 more

  • Humans2

Outcomes

1

Cognitive change over time

no changein humans1

1 study
  1. Social engagement has no effect on cognitive change over time in humans.

    Humans

    Social engagement, formal education, and cognitive outcomes among older adults in India: A longitudinal population-based study · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Sep 2026

Associations

2

General cognitive scores

upin humans1

1 study
  1. Social engagement is associated with general cognitive scores in humans (0.145 standard deviation units (95% CI: 0.076, 0.214)).

    Humansat baseline

    Social engagement, formal education, and cognitive outcomes among older adults in India: A longitudinal population-based study · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Sep 2026

Mortality

downin humans1

1 study
  1. Social engagement lowers the risk of mortality in humans.

    Humans15-yearmalesn = 1,741

    Cognitive function predicts all-cause mortality independent of social engagement among community-dwelling elderly Japanese men: a 15-year prospective cohort study · Environmental health and preventive medicine · 1 Jan 2026

Funding

National Institute on AgingUS$739.3kVeterans Affairs2 grants since 2023

Latest

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