1 paper2 findings
Intervertebral disc structure
downin rats1
Senofan protects against intervertebral disc structure in rats.
“reduced iron deposition and senescence, preserved disc structure, and showed favorable biosafety.”
Animalspuncture-induced intervertebral disc degenerationintervertebral disc
Targeted particles preserved disc structure in rats
Bioactive materials4 Oct 2026
Cellular senescence
downin cells1
Senofan decreases cellular senescence in cells.
“In vitro, SenoFAN reduced labile iron and oxidative stress, restored mitochondrial and lipid homeostasis, and suppressed lipid peroxidation and senescence.”
Cellsferro-aging modelnucleus pulposus cell
Targeted particles preserved disc structure in rats
Bioactive materials4 Oct 2026
An experiment in rats with puncture-induced disc degeneration tested iron-binding particles designed to target senescent cells, which have stopped dividing.An experiment in rats with puncture-induced disc degeneration tested iron-binding particles designed to target senescent cells, which have stopped dividing.