Amentoflavone

  • 1 lab in 1 country
  • Funders: Huazhong Agricultural University and 1 more
  • Model organisms1

Outcomes

2

Reactive oxygen species

downin worms1

1 study
  1. Amentoflavone decreases reactive oxygen species in worms.

    “promoted the nuclear translocation of DAF-16 and up-regulated the expression of antioxidant genes (e.g., sod-3, gst-3/4, hsp-16.48/12.6), leading to a significant reduction in intracellular ROS levels”

    Model organisms

    Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans

    Frontiers in pharmacology25 Nov 2025

More on Reactive oxygen species

Lifespan

upin worms1+64%

1 study
  1. Amentoflavone extends lifespan in worms (+63.81%).

    “Amentoflavone was identified and validated as a critical bioactive component, which alone extended lifespan by 63.81%”

    Model organisms

    Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans

    Frontiers in pharmacology25 Nov 2025

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