Amentoflavone
- 1 lab in 1 country
- Funders: Huazhong Agricultural University and 1 more
- Model organisms1
Outcomes
2Reactive oxygen species
downin worms1
1 study
Reactive oxygen species
downin worms1
Amentoflavone decreases reactive oxygen species in worms.
“promoted the nuclear translocation of DAF-16 and up-regulated the expression of antioxidant genes (e.g., sod-3, gst-3/4, hsp-16.48/12.6), leading to a significant reduction in intracellular ROS levels”
Model organisms
Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans
Frontiers in pharmacology25 Nov 2025
Lifespan
upin worms1+64%
1 study
Lifespan
upin worms1+64%
Amentoflavone extends lifespan in worms (+63.81%).
“Amentoflavone was identified and validated as a critical bioactive component, which alone extended lifespan by 63.81%”
Model organisms
Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans
Frontiers in pharmacology25 Nov 2025
Latest
1 in 12 monthsFrontiers in Pharmacology
Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans
Experiments in wormsInterventions