SARS-COV-2 nucleocapsid protein

SARS-COV-2 nucleocapsid protein has been studied in 1 paper since 2023: 1 observational study in people. The newest paper, Mar 9, 2023: “SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence”.

Intervention

1 paper studies it2 findingsUpdated

See all 1

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Central South University and 2 more
  • Humans1

What did studies of SARS-COV-2 nucleocapsid protein find?

2

Studies of SARS-COV-2 nucleocapsid protein measured 2 outcomes; the most studied are cognitive function (1 study) and cellular senescence (1).

Cognitive function

downin mice1

1 study
  1. SARS-COV-2 nucleocapsid protein impairs cognitive function in mice.

    “SARS-CoV-2 N protein-induced metabolic shifting toward glycolysis initiated a cascade of microglial senescence, which propagated cognitive impairment.”

    Animalsin mice

    The SARS-CoV-2 nucleocapsid protein induces microglia senescence-mediated cognitive impairment via Glycolysis

    Molecular medicine (Cambridge, Mass.)

Cellular senescence

upin mice1

1 study
  1. SARS-COV-2 nucleocapsid protein induces cellular senescence in mice.

    “SARS-CoV-2 N protein caused microglial senescence both in vivo and in vitro.”

    Animalsin mice

    The SARS-CoV-2 nucleocapsid protein induces microglia senescence-mediated cognitive impairment via Glycolysis

    Molecular medicine (Cambridge, Mass.)

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