SARS-COV-2 infection

Intervention2 papers4 findings

  • Humans2

Outcomes

2

IMMune Age indeX

downin humans1upin humans1Very low certainty

1 study
  1. SARS-COV-2 infection decreases IMMune Age indeX in humans.

    Humans4 weeks after infection (t3) after clinical recoveryn = 9

    Acute viral respiratory infections are not associated with an increased IMMune Age indeX (IMMAX) four weeks after infection: a prospective observational cohort study · Immunity & ageing : I & A · 22 Sep 2026

  2. SARS-COV-2 infection increases IMMune Age indeX in humans.

    Humansacute phase (t1)n = 9

    Acute viral respiratory infections are not associated with an increased IMMune Age indeX (IMMAX) four weeks after infection: a prospective observational cohort study · Immunity & ageing : I & A · 22 Sep 2026

IMMune Age indeX →

Functional capacity

no changein humans1Low certainty

1 study
  1. SARS-COV-2 infection has no effect on functional capacity in humans.

    Humans18-month longitudinal follow-up post-pandemic18 monthsn = 1,072

    Evolution of functional and mental status and quality of life in people aged 75 years and over after the COVID-19 pandemic in Spain: a prospective cohort study · BMC geriatrics · 7 Aug 2026

Associations

1

Anxiety

mixedin humans1Low certainty

1 study
  1. SARS-COV-2 infection is associated with anxiety in humans (p = 0.043).

    Humansdifferential longitudinal pattern over 18 months18 monthsn = 1,072

    Evolution of functional and mental status and quality of life in people aged 75 years and over after the COVID-19 pandemic in Spain: a prospective cohort study · BMC geriatrics · 7 Aug 2026

Anxiety →

Funding

National Institute on AgingUS$9.5mNational Institute of Neurological Disorders and StrokeUS$801.3k7 grants since 2022

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