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SARS-CoV-2 N-protein

SARS-CoV-2 N-protein has been studied in 1 paper since 2023: 1 observational study in people. The newest paper, Mar 9, 2023: “SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence”.

Intervention

1 paper studies it1 findingUpdated

See all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Associazione Italiana per la Ricerca sul Cancro and 8 more
  • 1 of 1 finding with company ties
  • Humans1

What did studies of SARS-CoV-2 N-protein find?

1

Studies of SARS-CoV-2 N-protein measured 1 outcome; the most studied are DNA repair (1 study).

DNA repair

downin cells1

1 study

  1. SARS-CoV-2 N-protein inhibits DNA repair in cells (SARS-CoV-2 infection).

    “SARS-CoV-2 N-protein impairs 53BP1 focal recruitment by interfering with damage-induced long non-coding RNAs, thus reducing DNA repair.”

    CellsSARS-CoV-2 infection

    SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence

    Nature cell biology

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