Pulsed electromagnetic field

Intervention

2 papers7 findings

  • 2 independent labs in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals2

Outcomes

7

Joint pathological damage

downin mice1

1 study
  1. Pulsed electromagnetic field decreases joint pathological damage in mice.

    “treatment with low-frequency PEMFs markedly inhibited NET formation, effectively delayed BMSC senescence, and ameliorated joint pathological damage in RA mice.”

    Animalsin rheumatoid arthritis mice

    Low-frequency pulsed electromagnetic fields inhibit the NETs/PADI4/MFN2 axis to ameliorate BMSC senescence in the treatment of rheumatoid arthritis

    Pathology, research and practice13 Jul 2026

Cellular senescence

downin mice1

1 study
  1. Pulsed electromagnetic field decreases cellular senescence in mice.

    “treatment with low-frequency PEMFs markedly inhibited NET formation, effectively delayed BMSC senescence, and ameliorated joint pathological damage in RA mice.”

    Animalsin rheumatoid arthritis mice

    Low-frequency pulsed electromagnetic fields inhibit the NETs/PADI4/MFN2 axis to ameliorate BMSC senescence in the treatment of rheumatoid arthritis

    Pathology, research and practice13 Jul 2026

More on Cellular senescence

Neutrophil extracellular trap formation

downin mice1

1 study
  1. Pulsed electromagnetic field decreases neutrophil extracellular trap formation in mice.

    “treatment with low-frequency PEMFs markedly inhibited NET formation, effectively delayed BMSC senescence, and ameliorated joint pathological damage in RA mice.”

    Animalsin rheumatoid arthritis mice

    Low-frequency pulsed electromagnetic fields inhibit the NETs/PADI4/MFN2 axis to ameliorate BMSC senescence in the treatment of rheumatoid arthritis

    Pathology, research and practice13 Jul 2026

More on Neutrophil extracellular trap formation

CTX-1

downin rats1

1 study
  1. Pulsed electromagnetic field decreases CTX-1 in rats.

    “decreased serum CTX-1 and elevated serum P1CP”

    Animals12 weeksmalesn = 8

    The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment

    Electromagnetic biology and medicine8 Feb 2024

More on CTX-1

NLRP3 inflammasome

downin rats1

1 study
  1. Pulsed electromagnetic field inhibits NLRP3 inflammasome in rats.

    “Furthermore, PEMF also dramatically inhibited NLRP3-mediated low-grade inflammation in the bone marrow”

    Animalsbone marrow12 weeksmalesn = 8

    The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment

    Electromagnetic biology and medicine8 Feb 2024

More on NLRP3 inflammasome

Bone loss

downin rats1

1 study
  1. Pulsed electromagnetic field decreases bone loss in rats.

    “The 12-week of PEMF showed significant mitigation of aging-induced bone loss and bone microarchitecture deterioration”

    Animalsbone12 weeksmalesn = 8

    The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment

    Electromagnetic biology and medicine8 Feb 2024

Bone mineral density

upin rats1

1 study
  1. Pulsed electromagnetic field increases bone mineral density in rats.

    “PEMF increased the bone mineral density of the proximal femur and L5 vertebral body”

    Animalsbone12 weeksmalesn = 8

    The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment

    Electromagnetic biology and medicine8 Feb 2024

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