Peucedanum japonicum

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: Korea Food Research Institute

Animals1

Outcomes

Mitochondrial biogenesis (PGC-1α)

upin mice1

1 study

Peucedanum japonicum activates mitochondrial biogenesis (PGC-1α) in mice.
“PJ supplementation promoted mitochondrial activity via PGC1α and stimulated mitochondrial biogenesis through the Nrf1-Tfam pathway.”
Animalsskeletal muscleeight weeks
Peucedanum japonicum Thunb. ameliorates age-related muscle loss by improving mitochondrial function in aged mice
GeroScience17 Feb 2026

More on Mitochondrial biogenesis (PGC-1α)

Muscle mass

upin mice1

1 study

Peucedanum japonicum increases muscle mass in mice.
“Increases in lean body mass, muscle weight, cross-sectional area (CSA), and the ratio of MHCII to MHCI fibers were observed.”
Animalsskeletal muscleeight weeks
Peucedanum japonicum Thunb. ameliorates age-related muscle loss by improving mitochondrial function in aged mice
GeroScience17 Feb 2026

Physical function

upin mice1

1 study

Peucedanum japonicum improves physical function in mice.
“PJ supplementation enhanced muscle strength and physicalrformance parameters, including treadmill endurance and stride length.”
Animalsskeletal muscleeight weeks
Peucedanum japonicum Thunb. ameliorates age-related muscle loss by improving mitochondrial function in aged mice
GeroScience17 Feb 2026

Latest

1 in 12 months

GeroScience17 Feb