AgingResearch.NewsJoin free

P21+ stromal cell removal

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: American Cancer Society and 7 more
  • Humans1

Outcomes

1

Tumor growth

downin mice1

1 study

  1. P21+ stromal cell removal decreases tumor growth in mice.

    “p21+ stromal cell removal blocked the SASP to reverse immune suppression and slow tumor growth.”

    Animalsprostate cancer

    p21-Positive Senescent Stromal Cells Promote Prostate Cancer Immune Suppression and Progression That Can Be Reversed by Senolytic Therapy

    Cancer discovery24 Oct 2025

Latest

Related