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Bcl-xl inhibitor

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: American Cancer Society and 7 more
  • Humans1

Outcomes

1

Prostate cancer

downin mice1

1 study

  1. Bcl-xl inhibitor inhibits prostate cancer in mice.

    “Senolytic BCL-xL inhibitor treatment could clear p21+ stromal senescent cells, reactivating antitumor CD8+ T-cell immunity and inhibiting prostate tumor progression in mice.”

    Animalsprostate cancer

    p21-Positive Senescent Stromal Cells Promote Prostate Cancer Immune Suppression and Progression That Can Be Reversed by Senolytic Therapy

    Cancer discovery24 Oct 2025

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