Multimodal interventions

Intervention1 paper2 findings

Outcomes

2

Bone loss

downin humans1

1 study
  1. Multimodal interventions decrease bone loss in humans.

    “Evidence supports multimodal interventions combining resistance exercise with optimized protein intake (1.2-1.5 g/kg/day) and nutritional supplements, including β-hydroxy-β-methylbutyrate, vitamin D and creatine, to attenuate muscle and bone loss.”

    Review

    Musculoskeletal decay and bone-muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures · Experimental physiology · 28 Sep 2026

Muscle loss

downin humans1

1 study
  1. Multimodal interventions decrease muscle loss in humans.

    “Evidence supports multimodal interventions combining resistance exercise with optimized protein intake (1.2-1.5 g/kg/day) and nutritional supplements, including β-hydroxy-β-methylbutyrate, vitamin D and creatine, to attenuate muscle and bone loss.”

    Review

    Musculoskeletal decay and bone-muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures · Experimental physiology · 28 Sep 2026

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