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Mulberroside a

Intervention

1 paper4 findings

PubChem 6443484ChEBI 177974

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab
  • Animals1

Outcomes

4

Inflammation

downin animals1

1 study

  1. Mulberroside a inhibits inflammation.

    “inhibit the overexpression of inflammatory factors in vivo”

    Animalsnaturally aging

    In vitro and in vivo investigation of the capacity of mulberroside A to inhibit senescence

    NPJ science of food30 Sep 2025

More on Inflammation

Telomerase depletion

downin animals1

1 study

  1. Mulberroside a decreases telomerase depletion.

    “mulberroside A was found to mitigate telomerase depletion in the blood of naturally aging animals”

    Animalsnaturally agingblood

    In vitro and in vivo investigation of the capacity of mulberroside A to inhibit senescence

    NPJ science of food30 Sep 2025

More on Telomerase depletion

Cellular senescence

downin animals1

1 study

  1. Mulberroside a decreases cellular senescence.

    “significantly reducing the levels of senescence biomarkers p16, p21, and Rb in both these endothelial cell types and in the hippocampus, kidney, spleen and liver of naturally aging animals”

    Animalsin naturally aging animals and angiotensin II-treated endothelial cells

    In vitro and in vivo investigation of the capacity of mulberroside A to inhibit senescence

    NPJ science of food30 Sep 2025

More on Cellular senescence

Endothelial cell proliferation

upin cells1

1 study

  1. Mulberroside a increases endothelial cell proliferation in cells.

    “mulberroside A promotes the proliferation of HMEC-1 and bEnd.3 endothelial cells”

    Cellsangiotensin II-induced senescence

    In vitro and in vivo investigation of the capacity of mulberroside A to inhibit senescence

    NPJ science of food30 Sep 2025

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