Mitotam

1. Mitotam decreases lung hypoxia in mice.

   “This was accompanied by reduced inflammatory and fibrotic gene expression, diminished myofibroblast accumulation, and alleviated lung hypoxia.”

   Animalsdiet-induced obesitylung

   Targeting Cellular Senescence as a Therapeutic Strategy to Attenuate Pulmonary Fibrosis Associated with Metabolic Syndrome

   Aging and disease·1 Jan 2026

1. Mitotam decreases senescence markers in mice.

   “In mice with diet-induced obesity, MitoTam improved glucose homeostasis, reduced adiposity, and markedly decreased senescence markers in lungs.”

   Animalsdiet-induced obesitylung

   Targeting Cellular Senescence as a Therapeutic Strategy to Attenuate Pulmonary Fibrosis Associated with Metabolic Syndrome

   Aging and disease·1 Jan 2026

More on Senescence markers

1. Mitotam improves glucose homeostasis in mice.

   “In mice with diet-induced obesity, MitoTam improved glucose homeostasis, reduced adiposity, and markedly decreased senescence markers in lungs.”

   Animalsdiet-induced obesity

   Targeting Cellular Senescence as a Therapeutic Strategy to Attenuate Pulmonary Fibrosis Associated with Metabolic Syndrome

   Aging and disease·1 Jan 2026