Mildronate

Mildronate has been studied in 3 papers since 2019: 1 trial in people, 1 in animals, 1 review. The newest paper, Jun 25, 2025: “Meldonium: current and emerging therapeutic applications”.

3 papers study it1 more mentions it5 findingsUpdated Jun 25, 2025

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Studies of mildronate measured 5 outcomes, among them learning and memory, neuronal apoptosis and cardiac, hepatic, and pulmonary tissue damage.

Learning and memory

upin reviews1

1 study

Mildronate improves learning and memory.
“Moreover, it inhibits neuronal apoptosis and facilitates cognitive functions, particularly learning and memory processes.”
Review
Meldonium: current and emerging therapeutic applications
Postepy biochemiiJun 25, 2025

neuronal apoptosis

downin reviews1

1 study

Mildronate inhibits neuronal apoptosis.
“Moreover, it inhibits neuronal apoptosis and facilitates cognitive functions, particularly learning and memory processes.”
Reviewneuron
Meldonium: current and emerging therapeutic applications
Postepy biochemiiJun 25, 2025

Cardiac, hepatic, and pulmonary tissue damage

downin reviews1

1 study

Mildronate protects against cardiac, hepatic, and pulmonary tissue damage (hypoxic conditions).
“By inhibiting mitochondrial β-oxidation of fatty acids under hypoxic conditions, meldonium exerts cytoprotective effects on cardiac, hepatic, and pulmonary tissues.”
Reviewhypoxic conditionscardiac, hepatic, and pulmonary tissues
Meldonium: current and emerging therapeutic applications
Postepy biochemiiJun 25, 2025

Bifidobacterium

upin mice1

1 study