Mifepristone
Intervention1 paper4 findingsPubChem 55245ChEBI 50692
- Animals1
Mouse lifespan
NIA ITPOutcomes
4Marrow adiposity
downin mice1Very low certainty
1 study
Marrow adiposity
downin mice1Very low certainty
Mifepristone decreases marrow adiposity in mice.
Animalsosteoporosis-hyperlipidemia comorbidity induced by ovariectomy and a high-fat dietbone marrow
Mifepristone improved bone formation in mice with bone loss · Journal of pharmaceutical analysis · 19 Mar 2026
Bone formation
upin mice1Very low certainty
1 study
Bone formation
upin mice1Very low certainty
Mifepristone increases bone formation in mice.
Animalsosteoporosis-hyperlipidemia comorbidity induced by ovariectomy and a high-fat dietbone
Mifepristone improved bone formation in mice with bone loss · Journal of pharmaceutical analysis · 19 Mar 2026
adipogenesis
downin mouse cells1Very low certainty
1 study
adipogenesis
downin mouse cells1Very low certainty
Mifepristone inhibits adipogenesis in mouse cells.
Cellsadipogenic differentiation conditionsbone marrow mesenchymal stem cell
Mifepristone improved bone formation in mice with bone loss · Journal of pharmaceutical analysis · 19 Mar 2026
osteogenic differentiation
upin mouse cells1Very low certainty
1 study
osteogenic differentiation
upin mouse cells1Very low certainty
Mifepristone increases osteogenic differentiation in mouse cells.
Cellsosteogenic differentiation conditionsbone marrow mesenchymal stem cell
Mifepristone improved bone formation in mice with bone loss · Journal of pharmaceutical analysis · 19 Mar 2026
Latest
1Mifepristone improved bone formation in mice with bone loss
In an experiment in mice with ovaries removed and fed a high-fat diet, the drug also reduced fat in bone marrow.In an experiment in mice with ovaries removed and fed a high-fat diet, the drug also reduced fat in bone marrow.