Melibiose

1. Melibiose activates autophagy in worms.

   “delaying the aging process by promoting autophagy (upregulation of lgg-1 and bec-1) and mitochondrial function”

   Model organisms

   Unveiling the anti-aging activities and mechanism of melibiose: insights from metabolomics and RT-qPCR analyses

   Free radical research·24 Aug 2025

More on Autophagy

1. Melibiose decreases reactive oxygen species in worms.

   “reduced lipofuscin and reactive oxygen species (ROS) accumulation, and increased antioxidant enzyme activity.”

   Model organisms

   Unveiling the anti-aging activities and mechanism of melibiose: insights from metabolomics and RT-qPCR analyses

   Free radical research·24 Aug 2025

More on Reactive oxygen species

1. Melibiose improves motility in worms.

   “melibiose enhanced resistance against heat and oxidative stress, improved nematode motility, reduced lipofuscin and reactive oxygen species (ROS) accumulation”

   Model organisms

   Unveiling the anti-aging activities and mechanism of melibiose: insights from metabolomics and RT-qPCR analyses

   Free radical research·24 Aug 2025

1. Melibiose extends lifespan in worms (+30.77%).

   “melibiose at concentrations of 100 μM, 150 μM, and 200 μM significantly increased nematode lifespan by 15.38%, 23.08%, and 30.77% respectively.”

   Model organisms200 μM

   Unveiling the anti-aging activities and mechanism of melibiose: insights from metabolomics and RT-qPCR analyses

   Free radical research·24 Aug 2025