Matrine

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funder: Basic and Applied Basic Research Foundation of Guangdong Province
  • Model organisms1

Outcomes

4

Aβ aggregation

downin worms1

1 study
  1. Matrine decreases Aβ aggregation in worms.

    “matrine not only reduces Aβ aggregation but also alleviates Aβ-mediated lipid metabolic disorder”

    Model organismsin an Alzheimer's disease C. elegans model

    Matrine Inhibits High-Glucose-Diet-Induced Fat Accumulation and Aβ-Mediated Lipid Metabolic Disorder via AAK-2/NHR-49 Pathway in Caenorhabditis elegans

    International journal of molecular sciences26 Mar 2025

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Physical fitness

upin worms1

1 study
  1. Matrine improves physical fitness in worms.

    “matrine increases physical fitness and lifespan through activating the AAK-2/NHR-49 pathway in high-glucose-diet nematodes”

    Model organismsin high-glucose-diet nematodes

    Matrine Inhibits High-Glucose-Diet-Induced Fat Accumulation and Aβ-Mediated Lipid Metabolic Disorder via AAK-2/NHR-49 Pathway in Caenorhabditis elegans

    International journal of molecular sciences26 Mar 2025

Lifespan

upin worms1

1 study
  1. Matrine extends lifespan in worms.

    “matrine increases physical fitness and lifespan through activating the AAK-2/NHR-49 pathway in high-glucose-diet nematodes”

    Model organismsin high-glucose-diet nematodes

    Matrine Inhibits High-Glucose-Diet-Induced Fat Accumulation and Aβ-Mediated Lipid Metabolic Disorder via AAK-2/NHR-49 Pathway in Caenorhabditis elegans

    International journal of molecular sciences26 Mar 2025

Fat content

downin worms1

1 study
  1. Matrine decreases fat content in worms.

    “matrine reduces the fat content and the DHS-3::GFP-labeled lipid droplets in high-glucose-diet N2 and transgenic LIU1 nematodes”

    Model organismsin high-glucose-diet nematodes

    Matrine Inhibits High-Glucose-Diet-Induced Fat Accumulation and Aβ-Mediated Lipid Metabolic Disorder via AAK-2/NHR-49 Pathway in Caenorhabditis elegans

    International journal of molecular sciences26 Mar 2025

More on Fat content

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