Low-molecular-weight hyaluronic acid
1 paper2 findings
- 1 lab in 1 country
- Funder: National Natural Science Foundation of China
- Animals1
Outcomes
2PI3K–AKT signalling
downin cells1
1 study
PI3K–AKT signalling
downin cells1
Low-molecular-weight hyaluronic acid inhibits PI3K–AKT signalling in cells.
“engagement of CD44 by LMW-HA suppressed AKT phosphorylation”
Cellsin vitronucleus pulposus
Biochemical and biophysical research communications6 Mar 2026
Cellular senescence
upin cells1
1 study
Cellular senescence
upin cells1
Low-molecular-weight hyaluronic acid induces cellular senescence in cells.
“HYAL2 overexpression and exogenous LMW-HA both induced nucleus pulposus (NP) cell senescence, inflammatory activation and ECM degradation.”
Cellsnucleus pulposus
Biochemical and biophysical research communications6 Mar 2026
Latest
1 in 12 monthsBiochemical and Biophysical Research Communications
HYAL2-generated low-molecular-weight hyaluronic acid promotes intervertebral disc degeneration via the CD44/AKT signaling axis
Experiments in micePI3K–AKT signalling