Low-inflammatory diet

Low-inflammatory diet has been studied in 3 papers since 2024: 2 observational studies in people, 1 review. The newest paper, Jan 24, 2025: “Optimizing orthobiologic therapies with exercise, diet, and supplements”.

Intervention

3 papers study it6 findingsUpdated

See all 3 papers on low-inflammatory diet

At a glance

The findings reach people, from one lab or study. 1 lab in 2 countries.

“a low-inflammatory diet (i.e. low IDI score) was associated with lower risk of all-cause mortality [hazard ratio (HR) = 0.82, 95% confidence interval (CI): 0.78 to 0.86]”
Association of a low-inflammatory diet with survival among adults: The role of cardiometabolic diseases and lifestyleClinical nutrition (Edinburgh, Scotland)2024doi:10.1016/j.clnu.2024.02.022

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 2 countries
  • Funders: Forskningsrådet för hälsa, arbetsliv och välfärd and 6 more
  • Humans2

What did studies of low-inflammatory diet find?

4

Studies of low-inflammatory diet measured 4 outcomes; the most studied are platelet count (1 study), chronic disease-free survival time (1) and multimorbidity accumulation (1).

Platelet count

upin humans1

1 study
  1. Low-inflammatory diet increases platelet count in humans.

    “Low inflammatory diets increase platelet counts and activity overall.”

    Review

    Optimizing orthobiologic therapies with exercise, diet, and supplements

    PM & R : the journal of injury, function, and rehabilitation

More on Platelet count

Chronic disease-free survival time

upin humans1

1 study
  1. Low-inflammatory diet is linked with higher chronic disease-free survival time in humans (+0.81 y (0.64, 0.97) IDI; +0.49 y (0.34, 0.64) EDIP).

    “The 50th percentile difference (95% CI) of chronic disease-free survival time was prolonged by 0.81 (0.64, 0.97) and 0.49 (0.34, 0.64) y for participants with a low IDI and EDIP, respectively.”

    Humans

    The association of a low-inflammatory diet with the trajectory of multimorbidity: a large community-based longitudinal study

    The American journal of clinical nutrition

Multimorbidity accumulation

downin humans1

1 study
  1. Low-inflammatory diet is linked with lower multimorbidity accumulation in humans (β IDI -0.033 (-0.036, -0.029); EDIP -0.006 (-0.010, -0.003)).

    “a slower multimorbidity accumulation (βIDI = -0.033, 95% CI: -0.036, -0.029; βEDIP = -0.006, 95% CI: -0.010, -0.003) compared with a high-inflammatory diet”

    Humans

    The association of a low-inflammatory diet with the trajectory of multimorbidity: a large community-based longitudinal study

    The American journal of clinical nutrition

Lifespan

upin humans1

1 study
  1. Low-inflammatory diet is linked with longer lifespan in humans (0.80 (0.55, 1.06) years delay in 10th percentile death time).

    “multi-adjusted 10th percentile difference (10th PD, 95% CI) of death time was delayed by 0.80 (0.55, 1.06; P < 0.001) years for participants with a low IDI score”

    Humansmedian 9.79 yearsn = 188,443

    Association of a low-inflammatory diet with survival among adults: The role of cardiometabolic diseases and lifestyle

    Clinical nutrition (Edinburgh, Scotland)

What is low-inflammatory diet linked with?

2

Studies link low-inflammatory diet with 2 measures, most often multimorbidity (1 study) and mortality (1).

Multimorbidity

downin humans1HR 0.84

1 study
  1. Low-inflammatory diet is linked with a lower risk of multimorbidity in humans (HR 0.84 (0.81, 0.86); HR 0.91 (0.89, 0.94)).

    “Adherence to a low-inflammatory diet was associated with decreased multimorbidity risk (hazard ratio [HRIDI] = 0.84, 95% confidence interval [CI]: 0.81, 0.86; HREDIP = 0.91, 95% CI: 0.89, 0.94)”

    Humansn = 102,424

    The association of a low-inflammatory diet with the trajectory of multimorbidity: a large community-based longitudinal study

    The American journal of clinical nutrition

More on Multimorbidity

Mortality

downin humans1HR 0.82

1 study
  1. Low-inflammatory diet is linked with a lower risk of mortality in humans (HR = 0.82, 95% CI: 0.78 to 0.86).

    “a low-inflammatory diet (i.e. low IDI score) was associated with lower risk of all-cause mortality [hazard ratio (HR) = 0.82, 95% confidence interval (CI): 0.78 to 0.86]”

    Humansmedian 9.79 yearsn = 188,443

    Association of a low-inflammatory diet with survival among adults: The role of cardiometabolic diseases and lifestyle

    Clinical nutrition (Edinburgh, Scotland)

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