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Losartan + pyrrolidine dithiocarbamate

Intervention

1 paper1 finding

PubChemPubChemChEBIChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

1

Aging nephropathy abnormalities

downin rats1

1 study

  1. Losartan + pyrrolidine dithiocarbamate prevents aging nephropathy abnormalities in rats.

    “Combined losartan+PDTC prevented all the observed abnormalities.”

    AnimalsMunich-Wistar ratskidneylosartan 50 mg/kg/d and PDTC 60 mg/kg/d3 monthsmalesn = 8

    Chronic Nuclear Factor-Kappa B Inhibition Prevents Experimental Aging Nephropathy

    Gerontology27 Nov 2024

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