Lifestyle modification program

Intervention1 paper2 findings

Outcomes

HbA1c

downin humans1−0.4%

1 study

Lifestyle modification program decreases HbA1c in humans (-0.4%).
“waist circumference (-6.3 cm), and HbA1c (-0.4%; all p”
Human trialprediabetes6 monthsn = 181
Lifestyle modification reduces phenotypic age in adults with prediabetes · Frontiers in aging · 10 Sep 2026

PhenoAge

downin humans1

1 study

Lifestyle modification program decreases PhenoAge in humans (-4.9 vs. +1.3 years).
“participants in the lifestyle modification program (LMP) showed a significant reduction in PhenoAge (-4.9 vs. +1.3 years; between-group p”
Human trialprediabetes6 monthsn = 181
Lifestyle modification reduces phenotypic age in adults with prediabetes · Frontiers in aging · 10 Sep 2026

Human trialPeer-reviewedAging clocks26 Sep

A six-month randomized trial in Arab adults found structured diet and exercise reduced biological age alongside metabolic markers.

Frontiers in aging · Alenezi A et al.