L-quebrachitol

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Ministry of Education of the People's Republic of China and 2 more

Model organisms1

Outcomes

Autophagy

upin worms1

1 study

L-quebrachitol induces autophagy in worms.
“QBC demonstrated significant autophagy induction, dependent on the regulation of AMPK and DAF-16”
Model organisms
L-Quebrachitol from Sea Buckthorn Leaves Extends Lifespan by Regulating Antioxidant Activity and Autophagy through AMP-Activated Protein Kinase/SIR-2.1/DAF-16 and IIS Signaling Pathways
Journal of agricultural and food chemistry24 Nov 2025

Latest

1 in 12 months

Journal of Agricultural and Food Chemistry24 Nov

L-Quebrachitol from Sea Buckthorn Leaves Extends Lifespan by Regulating Antioxidant Activity and Autophagy through AMP-Activated Protein Kinase/SIR-2.1/DAF-16 and IIS Signaling Pathways

Experiments in wormsInterventions

Paper

L-quebrachitol

Outcomes

Latest

L-Quebrachitol from Sea Buckthorn Leaves Extends Lifespan by Regulating Antioxidant Activity and Autophagy through AMP-Activated Protein Kinase/SIR-2.1/DAF-16 and IIS Signaling Pathways

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