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Idelalisib

Intervention

1 paper

  • Cells1

Latest

Cell Death & Disease·May 30

Combined inhibition of class 1-PI3K-alpha and delta isoforms causes senolysis by inducing p21WAF1/CIP1 proteasomal degradation in senescent cells

Experiments in human cellsInterventions
Paper

Related

  • Apoptosis1
  • CDKN1A1
  • Cellular senescence1
  • PI3K–AKT signalling1
  • PIK3CA1
  • PIK3CD1
  • Proteasome1
  • Ubiquitin–proteasome system1
  • Alpelisib1
  • Alpelisib + idelalisib1
  • Breast cancer1
  • Colorectal cancer1
  • Copanlisib1
  • Lung cancer1
  • p21WAF1/Cip11
  • p53–p21 pathway1
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