Hericium erinaceus
4 papers5 findings
- 2 independent labs in 2 countries
- Funders: Ministero dell’Istruzione, dell’Università e della Ricerca and 1 more
- 5 of 5 findings with company ties
- Animals2
Outcomes
4Lifespan
upin flies1upin mice1
1 study
Lifespan
upin flies1upin mice1
Hericium erinaceus extends lifespan in mice (maximum of 23%).
“extended the lifespan in both D. melanogaster and SAMP8 by a maximum of 32% and 23%, respectively, compared to the untreated controls.”
Animalslow, mid, or high doseerinacine A-enriched mycelian = 80
PloS one17 May 2019
Hericium erinaceus extends lifespan in flies (maximum of 32%).
“extended the lifespan in both D. melanogaster and SAMP8 by a maximum of 32% and 23%, respectively, compared to the untreated controls.”
Model organismslow, mid, or high doseerinacine A-enriched mycelian = 200
PloS one17 May 2019
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Hericium erinaceus decreases cellular senescence in mice.
“Parallelly, a significant decrease in crucial markers of inflammation and cellular senescence, i.e., CD45, GFAP, IL6, p62, and γH2AX, was demonstrated in the dentate gyrus and Cornus Ammonis hippocampal areas”
Animalsfrailstandardised extracthippocampustwo months
Biology28 Dec 2023
Inflammation
downin mice1
1 study
Inflammation
downin mice1
Hericium erinaceus decreases inflammation in mice.
“Parallelly, a significant decrease in crucial markers of inflammation and cellular senescence, i.e., CD45, GFAP, IL6, p62, and γH2AX, was demonstrated in the dentate gyrus and Cornus Ammonis hippocampal areas”
Animalsfrailstandardised extracthippocampustwo months
Biology28 Dec 2023
TBARS
downin mice1
1 study
TBARS
downin mice1
Hericium erinaceus decreases TBARS in mice.
“Moreover, erinacine A-enriched H. erinaceus mycelia decreased TBARS levels and induced the anti-oxidative enzyme activities of superoxide dismutase, catalase, and glutathione peroxidase.”
AnimalsSAMP8 miceerinacine A-enriched mycelian = 80
PloS one17 May 2019