P16-ASSOCIATED bioluminescence

1. Ganciclovir decreases P16-ASSOCIATED bioluminescence in mice (Partial but consistent reduction).

   “We demonstrate reproducible induction of p16-associated bioluminescence during wound healing, chemotherapy, and aging, as well as partial but consistent reduction following ganciclovir treatment.”

   Animalsp16-3MR mouse model

   Reproducible in vivo applications of the p16-3MR model in senescence research

   bioRxiv (Cold Spring Harbor Laboratory)·30 Jan 2026Preprint

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