FUNDC1 knockdown
Intervention1 paper1 finding
- Cells1
Outcomes
1Mitochondrial dysfunction
upin human cells1
1 study
Mitochondrial dysfunction
upin human cells1
FUNDC1 knockdown increases mitochondrial dysfunction in human cells.
“FUNDC1 knockdown aggravated photoaging-associated phenotypes, mitochondrial dysfunction, and altered autophagy/mitophagy-related activity”
Cellsunder UVA exposurehuman dermal fibroblast
FUNDC1 protects skin against UVA damage through mitophagy and P53 stability · Antioxidants (Basel, Switzerland) · 25 Aug 2026
Latest
1CellsMitochondria
FUNDC1 protects skin against UVA damage through mitophagy and P53 stability
Researchers identified a molecular pathway where FUNDC1 preserves mitochondrial quality and works with BAZ1B to regulate P53 during skin photoaging.