Food restriction

1. Food restriction increases IL-6 in O. aries.

   “Food-restricted animals displayed distinct CSF inflammatory profiles, with IL-1α and IL-6 exceeding obese levels at several time points”

   Animalsin food-restricted ewescerebrospinal fluid14-weekfemales

   Tracking CSF inflammatory signatures in an ovine model of leptin resistance

   Scientific reports·17 Jul 2026

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1. Food restriction decreases collagen biomarker of aging in rats.

   “In RW and PW, the increase in the composite parameter was retarded to the same extent.”

   Animalsmales

   Voluntary exercise and mild food restriction effectively retard the collagen biomarker of aging

   Aging clinical and experimental research·1 Dec 2003

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1. Food restriction increases gastric ulcer in mice (13 to 34% vs 5 to 9%).

   “Ulcers, ranging in incidence with ad libitum feeding from 5 to 9% and with food restriction from 13 to 34%”

   Animalsthroughout lifestomachfemales

   Spontaneous nonneoplastic gastric lesions in female Han:NMRI mice, and influence of food restriction throughout life

   Veterinary pathology·1 May 1987

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1. Food restriction decreases adenomatous hyperplasia of the gastric fundus in mice.

   “the frequency increased with age and was significantly reduced by food restriction.”

   Animalsthroughout lifestomachfemales

   Spontaneous nonneoplastic gastric lesions in female Han:NMRI mice, and influence of food restriction throughout life

   Veterinary pathology·1 May 1987

More on Adenomatous hyperplasia of the gastric fundus