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Dpc

Intervention

1 paper studies it3 findings

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Humans1

Outcomes

3

Fibrosis

downin mice1

1 study

  1. Dpc decreases fibrosis in mice.

    “alleviating inflammation and fibrotic changes in BDL mice.”

    AnimalsBDL miceliver

    Mitochondrial dysfunction-mediated hepatocyte senescence is involved in cholestatic liver injury

    Free radical biology & medicine

Inflammation

downin mice1

1 study

  1. Dpc decreases inflammation in mice.

    “the elimination of senescent hepatocytes by a new senolytic DpC improves liver function, alleviating inflammation and fibrotic changes in BDL mice.”

    AnimalsBDL miceliver

    Mitochondrial dysfunction-mediated hepatocyte senescence is involved in cholestatic liver injury

    Free radical biology & medicine

More on Inflammation

Liver function

upin mice1

1 study

  1. Dpc improves liver function in mice.

    “Importantly, the elimination of senescent hepatocytes by a new senolytic DpC improves liver function, alleviating inflammation and fibrotic changes in BDL mice.”

    AnimalsBDL miceliver

    Mitochondrial dysfunction-mediated hepatocyte senescence is involved in cholestatic liver injury

    Free radical biology & medicine

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