Decitabine

  • 2 independent labs in 2 countries
  • Funders: China Postdoctoral Science Foundation and 5 more
  • Model organisms2
  • Cells1

Outcomes

2

Epigenetic age

downin mouse cells1

1 study
  1. Decitabine decreases epigenetic age in mouse cells (from 22 to 10 months).

    “treatment with the DNA methylation inhibitor decitabine reduced the methylation age of organoids from 22 to 10 months”

    Cellsin cultureintestinal organoids

    Modeling age-related methylation changes in vitro with intestinal organoids

    BMC biology6 Mar 2026

More on Epigenetic age

Cellular senescence

downin human cells1

1 study
  1. Decitabine decreases cellular senescence in human cells.

    “reversal of PRKAG2 epigenetic silencing with decitabine mitigated PDLSC senescence by suppressing ATM signaling.”

    Cells

    Multi-omics approach reveals TGF-β signaling-driven senescence in periodontium stem cells

    Journal of advanced research30 Dec 2024

More on Cellular senescence

Latest

Nov 2025: 0Dec 2025: 2Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 03 in 12 months